The Ukrainian manufacturer of veterinary medicines, BIOTESTLAB, is expanding its line of antibacterial agents for industrial poultry farming and introducing FLORTRIM — an oral solution with dual antibacterial action.
The new drug is designed for use in broiler production for bacterial diseases that require a comprehensive approach to therapy, in particular for infections of respiratory, enteral and systemic localisation.
Dual action for complex cases
FLORTRIM contains two active ingredients: enrofloxacin (100 mg/ml) and trimethoprim (50 mg/ml). Enrofloxacin belongs to the fluoroquinolone class and acts by inhibiting bacterial DNA gyrase, thereby disrupting bacterial DNA replication. The agent is active against Gram-positive (Staphylococcus spp., Streptococcus spp., Clostridium spp.) and Gram-negative (Pseudomonas spp., E. coli, Haemophilus spp., Salmonella spp., etc.) bacteria, and also acts on mycoplasma (Mycoplasma spp.) and chlamydia (Chlamydia spp.).
Trimethoprim is a broad-spectrum antimicrobial agent from the group of diaminopyrimidines. The mechanism of action is to inhibit bacterial dihydrofolic acid reductase, thereby blocking the synthesis of folic acid, which is necessary for bacterial growth and development. The drug has a bacteriostatic effect on Gram-positive (Staphylococcus spp., Streptococcus spp.) and Gram-negative (E. coli, Salmonella spp., Pasteurella spp., Enterobacter spp., etc.) microorganisms.
The combination of two mechanisms of action provides a comprehensive antibacterial effect against microorganisms sensitive to enrofloxacin and trimethoprim, and allows the drug to be used in situations where broader coverage of bacterial pathogens and systemic action are important.
Systemic action where it is needed
FLORTRIM is intended for the treatment of broilers with colibacillosis, salmonellosis, necrotic enteritis, streptococcosis, haemophilia and mycoplasmosis caused by microorganisms sensitive to the active ingredients of the drug.
The drug covers key groups of bacterial infections relevant for broiler production:
- intestinal infections: E. coli, Salmonella spp., Clostridium spp.;
- respiratory infections: Haemophilus spp., Mycoplasma spp.;
- systemic complications: Streptococcus spp., as well as systemic forms of E. coli and Salmonella spp.
After oral administration, enrofloxacin is rapidly absorbed from the digestive tract and well distributed in body tissues and fluids. The maximum concentration of enrofloxacin in the blood is reached 60–120 minutes after administration. Trimethoprim is also rapidly absorbed after oral administration, is well distributed in body tissues and fluids, and, in poultry, has a bioavailability of 80%.
This makes the drug relevant for the treatment of bacterial infections, where rapid absorption, systemic distribution and achievement of therapeutic concentrations in tissues are important.
Convenience of use in broiler production
FLORTRIM is used orally with drinking water at a dose of 0.5–1 ml of the drug per 1 litre of drinking water for 3–5 days. During the treatment period, water with the drug should be the only source of drinking water for poultry.
The withdrawal period for poultry meat is 11 days.
At the start of sales, the drug is available in 1000 ml polymer bottles.
Development of the portfolio for industrial poultry farming
The launch of FLORTRIM is part of the systematic development of the BIOTESTLAB portfolio for poultry farming. The company continues to expand the line of veterinary solutions for the prevention, control and treatment of poultry diseases, focusing on the needs of modern intensive production.
In 2026, the company launched SPECTOLIN, a powder for oral administration based on spectinomycin 44.4% and lincomycin 22.2%, for the treatment of complex bacterial infections in pig and poultry farming.
Detailed information and instructions for use are available on the official website of BIOTESTLAB: DOWNLOAD
FLORTRIM is officially registered in Ukraine. The owner of the registration certificate is BIOTESTLAB LLC.
