SPECTRAN

antibiotic and antinflamatory injectable suspension of Amoxicillin – 150.0 mg, Betamethasone – 0.5 mg

SPECTRAN

antibiotic and antinflamatory injectable suspension of Amoxicillin – 150.0 mg

CattleCat breedingPigsDog breeding
SPECTRAN
10 ml
100 ml

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Description

Suspension of white-and-cream to light yellow colour.

Composition

1 ml of preparation contains following active substances:

Amoxicillin (as Amoxicillin trihydrate) – 150.0 mg;

Betamethasone (as Betamethasone dipropionate) – 0.5 mg;

Additional ingredients: Benzyl alcohol, Butylhydroxytoluene, Butylhydroxyanisole, Aluminum stearate, Propylene glycol dicaprylate/dicaprate

Pharmacological properties

ATC vet code QJ01 – antibacterial veterinary preparations for systemic use. QJ01CA04 – Amoxicillin.

Amoxicillin is an antibiotic of wide bactericidal action belonging to the group of Aminopenicillins. It blocks the synthesis of bacterial cell walls, inhibits an enzyme activity of transpeptidase and carboxypeptidase, causing the violations of osmotic pressure in bacterial cell that leads to the death of the bacteria at the stage of their growth. Preparation is active against Gram-positive and Gram-negative bacteria(Streptococcus spp., Pasteurella spp., Haemophilus spp., Bacillus anthracis, Actinomyces spp., Clostridium spp., Corynebacterium spp., Erysipelothrix rhusiopathiae, Listeria monocytogenes, Actinobacillus spp., Bordetella bronchiseptica, Fusobacterium spp., Moraxella spp., Proteus mirabilis, Salmonella spp.).

Peak serum concentration is reached in 1-2 hours after the injection and remains on therapeutic levels within 48 hours.

Amoxicillin is practically not metabolized. Excreted mainly in the urine, less in milk and bile.

Betamethasone belongs to the group of synthetic corticosteroids (adrenal hormones), it has anti-inflammatory, antipruritic, anti-allergic, anti-proliferative effects.

Betamethasone dipropionate has a prolonged effect due to slow absorption. Betamethasone bioavailability is approximately 72%, half-life is 5.6 hours, 64% of it binds to plasma protein.

It is metabolised in the liver, excreted by kidneys and only a small fraction is excreted in the bile.

Administration

Treatment of cattle, pigs, dogs and cats in case of digestive tract diseases (enteritis, gastroenteritis, gastroenterocolitis), respiratory diseases (bronchitis, pneumonia, rhinitis) and urinogenital tract diseases (metritis, endometritis, mastitis, agalactia, cystitis, urethritis, pyelonephritis), in case of joints, skin and soft tissue diseases (umbilical infection, wounds, abscesses, inflammation); and for the treatment of animals suffering from leptospirosis, actinomycosis, swine erysipelas, parainfluenza, paratyphoid, caused by pathogens susceptible to Amoxicillin.

Route of administration and dosages

Intramuscularly or subcutaneously only once at a dose of 1 ml per 10 kg body weight. If necessary, the product is administered again in 48 hours.

Contraindications

Do not administer to rabbits, guinea pigs, hamsters and other rodents and to animals with hypersensitivity to amoxicillin, betamethasone or other drug ingredients.

Do not administer this product to pregnant cows within last month of pregnancy, and during the first third of sows’ gestation.

Do not administer to weak, emaciated animals and to animals with severe renal insufficiency.

Do not use together with bacteriostatic antibiotics (tetracycline, chloramphenicol, erythromycin, etc.).

Precautions

Thoroughly shake before use.

Should not be injected more than 20 ml to cattle, and more than 5 ml to pigs and dogs in one site.

Not administered intravenously.

Withdrawal period

For meat: 14 days after last treatment, for milk: 3 days after last treatment.Meat and milk received before this time should be disposed or fed to non-productive animals, depending on conclusion of the veterinarian.

Storage conditions

Store in a dry, dark places, out of the reach of children, at +5 to +25° С.

Shelf life

24 months. After the first opening: 28 days if kept in a dry, dark place at +5 to +25° С.