FLOXY-SPRAY MAX

Wound healing antimicrobial spray for external use
fluorfenikol — 2,5 g
prednisolone acetate — 0,1 g

FLOXY-SPRAY MAX

Transparent liquid, colorless or light yellow color

Cat breedingDog breeding

COMPOSITION

100 ml of the drug contains active ingredients:

Florfenicol – 2.5 g;

Prednisolone acetate – 0.1 g.

Excipients: methylpyrrolidone, polyvinylpyrrolidone, ethyl alcohol, isopropyl alcohol, propylene glycol, glycerin, dimethyl sulfoxide.

PHARMACEUTICAL FORM

Transparent liquid, colorless or light yellow color.

PHARMACOLOGICAL PROPERTIES

ATC vet code QD06A – topical antibiotics.

Florfenicol is a thiamphenicol derivative in which the hydroxyl group is replaced by a fluorine atom, which provides its antibacterial activity against acetyltransferase-synthesizing bacteria.

Florfenicol is effective as bacteriostatic against gram-positive (Streptococcus spp., Staphylococcus spp.) and gram-negative bacteria (Fusobacterium necrophorum, Bacteroides melaninogenicus, Pasteurella spp., Salmonella spp., Proteus spp., Pseudomonas spp., Haemophilus spp.), as well as against Mycoplasma spp., Rickettsia spp., Chlamydia spp.

Florfenicol inhibits protein synthesis in bacterial cells. In the protoplasm, it binds to the 70S-subunits of ribosomes, inhibits the enzymatic activity of peptidyl transferase, thus inhibiting the synthesis of proteins in the ribosomes of the corresponding bacteria.

When used externally, Florfenicol acts locally and almost does not penetrate into the circulatory system. In animals’ bodies, it is metabolized to form the florfenicol amine metabolite. Florfenicol and its metabolites are excreted mainly in the urine, and less in the feces.

Prednisolone is a synthetic glucocorticoid. It has anti-inflammatory, anti-allergic, and anti-exudative effects. The anti-inflammatory effect is due to the inhibition of the metabolism of arachidonic acid and the release of inflammatory mediators.

When applied topically, Prednisolone is absorbed, and released into the bloodstream. 90% of Prednisolone in plasma is bound (with transcortin and albumin). It biotransforms by oxidation, predominantly in the liver; oxidized forms undergo glucuronidation and sulfatization. It is excreted in the urine and feces in the form of metabolites, and partially as unchanged.

ADMINISTRATION

Treatment of dogs, cats and rabbits of decorative breeds with dermatitis, panaritium, pyoderma, eczema, as well as with wounds (including after castration), with scratching, bites, bruises, ulcers caused by pathogens susceptible to Florfenicol.

DOSAGE

Before using the drug, the affected area is thoroughly cleaned of exudates, necrotic tissues.

First, shake the bottle and, holding it at a distance of 5-10 cm from the surface of the damaged skin area, press the sprayer 1-2 times and treat the area approx. 5x5 cm.

It is recommended to apply the drug every 12 hours until complete healing.

The duration of treatment depends on the extent of the lesion and the rate of healing.

CONTRAINDICATIONS

Do not administer to animals with hypersensitivity to the drug components.

Do not use concomitantly with thiamphenicol or chloramphenicol.

SIDEEFFECTS

Allergic reactions are possible with individual hypersensitivity to the components of the drug.

PRECAUTIONS

Do not allow the drug to get into the eyes of animals and humans. Do not allow the animal to lick the drug for 5 minutes. Shake the bottle with the drug before use.

Treatment of animals with the drug should be carried out as far as possible from open flames and heating devices.

PACKAGE

Bottles made of polymeric materials with a spray of 9, 30; 50; 100; 200; 250; 500 ml.

SHELF LIFE

2 years.

Expiration date after first use: before the expiration date.

STORAGE CONDITIONS

Dark place, out of the reach of children, between 5°С to 25° С.

For veterinary use only!