antibiotic injectable solution
florfenicol 30%


Clear solution of light yellow to yellow color.



1 ml of the drug contains an active substance:

Florfenicol – 300 mg.

Excipients: methylpyrrolidone, ethyl alcohol, propylene glycol, polyethylene glycol.

Pharmacological properties

ATC vet classification code QJ01 – antibacterial veterinary drugs for systemic use. QJ01MA90 – Florfenicol.

Florfenicol is derivative of thiamphenicol, in which hydroxyl group is substituted by fluorine atom that induces its antibacterial activity against acetyltransferase synthesizing bacteria, susceptible to chloramphenicol.

Florfenicol has bacteriostatic effect on Gram-positive and Gram-negative bacteria, such as: Pasteurеlla spp., Actinobacillus pleuropneumoniae, Bordetella bronchiseptica, Salmonella spp., Escherichia coli, Haemophilus spp., Proteus spp., Staphylococcus spp., Streptococcus spp., Shigella spp., Klebsiella spp., Enterobacter spp., Aeromonas spp., Flexibacter spp., Vibrio spp. etc.

In protoplasm, it binds to 70S-ribosomal subunits, inhibits the enzymatic activity of peptidyl transferase, thereby breaking the protein synthesis in the ribosomes of the respective bacteria.

After administration, it is well distributed in the body. It reaches high concentrations in the lungs, kidneys, as well as in the muscles, intestines, heart, liver and bile, spleen, and blood serum.

In pigs after a single intramuscular injection of the drug, the maximum concentration of florfenicol in the serum was observed in the range of 3.7-3.8 μg/ml.

After intramuscular administration to cattle at a dose of 20 mg/kg body weight, the therapeutic concentration of florfenicol in blood plasma was retained for 48 hours. The maximum concentration in serum was reached after 3.3 hours after administration and was 3.37 μg/ml. The average concentration of florfenicol in serum after 24 hours after intramuscular administration was 0.77 μg/ml. The average elimination half-life is 18.3 hours.

It is excreted mainly by the kidneys unchanged, by glomerular filtration, as well as with bile, inactivated by the formation of chelate compounds, and then excreted with feces.


Treatment of cattle, sheep, goats, pigs in case of diseases of the digestive canal, respiratory system, and genitourinary system, caused by pathogens, susceptible to Florfenicol.

Route of administration and dosages

Cattle, sheep, and goats: intramuscularly at a dose of 1 ml of the drug per 15 kg of animal b.w. twice with an interval of 48 hours; subcutaneously – once at a dose of 2 ml of the drug per 15 kg of b.w.

Pigs: intramuscularly at a dose of 1 ml of the drug per 20 kg of animal b.w. twice with an interval of 48 hours.


Do not administer to animals with a hypersensitivity to the drug components.

Do not administer to non-target animals.

Do not administer to sows, goats, and sheep during pregnancy, as well as to cows in the first three months of pregnancy.

The drug is not used during lactation.

Do not use simultaneously with thiamphenicol or chloramphenicol.

Do not administer to adult boars intended for reproduction.


Side effects

Cattle: during treatment, there may be a decrease in appetite and water intake, the occurrence of diarrhea. Appetite is quickly and completely restored immediately after treatment is discontinued. Sometimes slight swelling may appear at the injection site, which disappears within 28 days.

Pigs: redness and/or swelling of the perineum, diarrhea after administration of the drug may appear. Changes at the injection site are reversible and completely disappear within 3 weeks.

Special warnings

If the dose of the drug to be injected exceeds 10 ml for cattle, 5 ml for pigs, sheep, and goats, then it is divided and injected into different places.

Withdrawal period

Slaughter of the animals for meat is allowed in 30 days (cattle, sheep, goats with intramuscular administration), in 44 days (cattle, sheep, goats with subcutaneous administration), and 18 days (pigs) after the last treatment. Meat and milk received before the specified time should be disposed or fed to non-productive animals, depending on the conclusion of the veterinarian.

Presentation and packaging

Glass vials closed by rubber stoppers under aluminum caps of 10, 50 and 100 ml.

Storage conditions

Store in a dark places, out of the reach of children, at +5 to +25° С.

Shelf life

24 months. Once the vial is opened: 28 days if stored in a dark place at +5° to +25°С.