DANOXAN-25

antibiotic injectable solution
danofloxacin 2.5%

DANOXAN-25

antibiotic injectable solution vials

CattlePigs
DANOXAN-25
10 ml
50 ml
100 ml

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Composition

1 ml of the preparation contains:

active substance Danofloxacin – 25 mg; additional ingredients.

Pharmacological properties

Danofloxacin is a chemotherapeutic agent of a broad-spectrum belonging to the group of fluoroquinolones 3rd generation.

Mechanism of action of Danofloxacin is based on deactivation of bacterial enzyme of DNA gyrase and topoisomerase IV, resulting in inhibition of bacterial DNA replication. Product is active against Gram-positive and Gram-negative microorganisms such as Staphylococcus aureus, Streptococcus pyogenes, Escherichia colі, Enterobacteriaceae spp., Pasteurella spp., Haemophilus spp., Acti spp., Brucella spp., Salmonella spp., Bordetella bronchiseptica, Proteus vulgaris, Pseudomonas aeruginosa, etc., and Mycoplasmas.

When administered parenterally maximum concentration of Danofloxacin in blood is achieved approx. in 1 hour, and therapeutic concentration is maintained for 24 hours.

Danofloxacin has a high level of distribution in the body of animals. Concentration in tissues and organs is significantly higher than in serum. Body organs, in which the highest concen- tration is observed: lungs, liver, kidneys, intestines and muscles. Danofloxacin is partially metabolized in liver and excreted with urine and bile.

Administration

Treatment of catt and pigs in case of the respiratory and digesti e tract diseases caused by pathogens suscepti to Danofloxacin.

Routes of administration and dosages

Animal species

Dosage

Routeof administration

Cattle

0.5 ml /10 kg body weight once daily for 3 days

Subcutaneously

Pigs

Intramuscularly

If necessary, the treatment can be prolonged for a further 2 days.

In one injection site can be administered not more than 20 ml for cattle and 5 ml for pigs.

Withdrawal period

Slaughter of animals for meat is permitted in 5 (cattle) and 3 days (pigs) after the last treatment. Milk for human consumption is allowed in 4 days after the last treatment. Meat and milk received before this period should be disposed or fed to non-productive animals, depending on conclusion of veterinarian.

Self life

24 months. After first opening – 14 days if stored in dark place at +5 to +25° С.

Storage conditions

Store in dry, dark places, out of the reach of children at +5 to +25° С.